An Indian originscientist from the University of Newcastle’s Nutraceuticals Research Group has found that curcumin in turmeric in combinatin with Omega-3 can delay type-2 diabetes and even prevent it effectively, if taken regularly.
Professor Manohar Garg says the cause of the type 2 diabetes is due to systemic inflammation that affects secretion fuction of pancreas glands and turmeric can act on it effectively. He is planning to recruit 80 participants to conduct his new clinical study to find out whether the Indian spice mixed with Omega-3 can act as a preventive medicine for diabtes onset.
“We want to nip the inflammation in the bud. This study will use two bioactive compounds that we find in food – curcumin and omega-3 fat. Both are very important anti-inflammatory agents,” Garg said.
Curcumin, present in turmeric, which is part of the ginger family, has several healing properties and is a key component in ancient Hindu Ayurvedic treatment for many ailments including diabetes combinations. It is used in traditional medicine to heal bruises, sprains, wounds and inflammation.
Since the modern food habits have dropped down the in-take of turmeric in Indian traditional food items, “it parallels with a significant rise in type 2 diabetes cases. In fact the disease is now an epidemic in India and may soon be the number one health burden,” said Garg.
In a randomised control trial both compounds — curcumin and omega-3 will be tested on four groups — one will get curcumin only, the second will get omega-3 fat only, the third will receive both, and the fourth will be a control group, Garg explained.
Prof. Garg is planning capsules containing 200 milligrammes of curcumin and one gram of omega-3 fat and those in pre-diabetes stage with impaired glucose tolerance or impaired fasting glucose, and aged between 30 and 70, will be recruited for the experiment, he said.
“The anti-inflammatory mechanisms surrounding curcumin and omega-3 fats are different, so we want to test if they complement each other and have treatment synergies beyond their individual effects,” Garg said, pointing out the safety of the combination which is free from any side-effects.
In November 2012, Professor Garg was awarded the 2012 Nutrition Society of Australia Medal for his outstanding record in the field of human nutrition.
“My research has had an important impact on human health but this award was also measured on the overall impact of my research including quality and quantity of research publications, links with stakeholders including those in the industry, supervision of Research Higher Degree students and contributions to the Activities of the Nutrition Society of Australia,” he said.
Professor Garg was also awarded the prestigious 2012 Professor Austin Doyle Medal in recognition of his outstanding contributions in cardiovascular sciences, especially the role of nutrition in preventing complications of cardiovascular disease. “My research on long chain omega-3 fatty acids and sex-based responses of nutrition interventions on cardiovascular disease acclaimed world-wide attention.
Armed with his specialization in both key walks of research arena, Prof. Garg is planning a comination drug to prevent the incidence of diabetes using the Indian herbal, known for its therapeutic properties.
Diabetes is taking the status of a potential epidemic in India with more than 62 million diabetic individuals currently diagnosed with the disease. In 2000, India with 31.7 million diabetics topped the world with the highest number of people with diabetes mellitus followed by China (20.8 million) with the United States (17.7 million) in second and third place respectively.
According to WHO, the prevalence of diabetes is predicted to double globally from 171 million in 2000 to 366 million in 2030 with a maximum increase in India. It is predicted that by 2030 diabetes mellitus may afflict up to 79.4 million individuals in India, while China (42.3 million) and the United States (30.3 million).