Researcher have found that garlic and broccoli help improving treatment against cancers, especially melanoma and prostate cancer by slowing down the body immune system’s over-response.
The team from the University of Copenhagen have found that selenium, naturally found in garlic and broccoli, is the main ingredient which helps the process. Melanoma, prostate cancer and certain types of leukaemia often weaken the body by over-activating the natural immune system.
The immune system is designed to remove things not normally found in the body but different cancer cells contain mechanisms that block the immune system’s ability to recognise them, so they can freely continue multiplying and spreading cancer to other parts of the body.
Stimulating molecules of certain cancer cells over-activate the immune system and cause it to collapse, when it is most needed in some phases of cancer treatment.
“We have now shown that certain selenium compounds which are naturally found in garlic and broccoli effectively block the special immuno-stimulatory molecule that plays a serious role for aggressive cancers such as melanoma, prostate cancer and certain types of leukaemia,” said professor Soren Skov of the University of Copenhagen in Denmark.
In the long term, consuming garlic and broccoli may improve cancer treatment, he added. “If we can find ways to slow down the over-stimulation, we are on the right track. The new results are yet another small step towards better cancer drugs with fewer adverse effects,” Skov said.
The findings have been published in the latest Journal of Biological Chemistry.